I have a list of ABI microarray probes with "signal values". How can I tell if it's been background corrected?

Question

[Kristin Muench]

Hello,

I'm working with the supplementary raw data downloaded from GSE28551. It's unclear what each column in this supplementary file means, I unfortunately can't reach the original author/database point of contact, and since the product has been discontinued, I haven't had much luck getting information about the original file processing.

I'm trying to figure out if one data column, "Signal", has already been background corrected, so that all I would need to do next is apply quantile normalization.

Is there a way I could tell if this data has already been background corrected by plotting it?

Thank you for your help!

The column names, for the curious:

• Probe_ID
• Signal
• SDEV
• Flags
• S_N
• Sample_name
• Assay_Normalized_Signal
• CV
• probe_type