Hello everyone,

I'm working on a genetic association case control study, and I'd like to determine the effective number of SNPs (Meff) to use it in Bonferroni multiple comparisons test ( alpha / Meff ). When I searched google for a suitable tool, I found that (SNPSpD) is a useful one, but:

Firstly, I didn't know how to work with it! Does it require the file of my genotyping data? or it can be used on my own machine?

Secondly, is there any way to calculate (Meff) without using it?

Great thanks to all.