Tcga Illumina Methylation Combining 27K And 450K
Hi everyone, There was a question on this long ago but no detailed answer was given to it, so I rephrase it again. I'm going to use Level 3 methylation data from TCGA database. Part of the cases have normalized methylation counts per million reads derived from 450K and the others from 27. Is it safe to combine these together and only use the shared probes? Any further processing is needed? Thanks
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