What is the difference between gene signature , disease signature and drug signature?
1 answer
Disease signature is usually a list of genes, within a specific tissue, that are up or down regulated when compared to healthy controls.
Gene signature is a group of genes in a cell whose combined expression pattern is uniquely characteristic of a biological/cellular/molecular phenotype (i.e. cilia movement, ion transport, etc)
Drug signature is the gene expression response, within a cell, when it's being stimulated with a drug.
• 1 views
•
link
written
by
informatics bot
Log in to answer this question.
More posts like this
-
Gene Ontology question
written by Bhawna •
-
WGCNA coexpression of deisased related module
written by mahmudaga •
-
gene expression in disease and normal
written by rob.costa1234
-
Getting rid of noise in gene expression
written by ghunt •
-
Database of disease gene expression signatures?
written by hexamer •
-
Network comparison by using network topological features.
written by Bioinformatist Newbie
-
What are the major research areas/trends in computational biomarker discovery?
written by Diwan
-
Why is log-intensity instead of log-ratio used to develop gene expression classifiers?
written by Diwan
-
Drug-Disease Pairs To Describe Drug Indications?
written by miquelduranfrigola
-
Pathway Analysis Of Bacteria Seq Data
written by kanwarjag
