ORegAnno Strand Specificity
I'm checking out the DB files of ORegAnno and I notice that there is a 1:3 ratio of (-) strand TFBSs vs (+).
I was expecting most data not to actually have strand info (*), since many techniques are unstranded and many TFs affect loci on both strands.
What would you suggest? Keep strand info as it is or remove it for downstream analyses?
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