I want to find differentially expressed miRNAs between 4 groups

Hi,

I have some miRNA expression data and I want to identify the differentially expressed miRNAs between 4 separate subtypes. Is this possible with DeSeq2 or Limma?

Thanks in advance

differential-expression r microrna limma

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updated 4.0 years ago by Ram

• written 10.5 years ago by Nev •

1 answer

This all depends on your platform, preprocessing steps, normalisation, etc. Once your data is normalised, and QC has been carried out, Limma is a suitable suite for identifying differential expression.

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updated 6.6 years ago by Ram

• written 10.5 years ago by andrew.j.skelton73

Okay, thank you Andrew. Yes, it is a miRNA expression matrix and quantile normalized.

• 0 views • link

updated 6.6 years ago by Ram

• written 10.5 years ago by Nev •

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