I think you need to elaborate on what you are trying to achieve in order to get some useful answers..

By using the appropriate subject identifiers. For a clearer response, please phrase your question better.

Hello akhilvbioinfo!

We believe that this post does not fit the main topic of this site.

Your post and comment history suggests you ask questions along similar lines yet do not provide details. Question closed until you elaborate on the topic. This might be of help: http://www.ploscompbiol.org/article/info:doi%2F10.1371%2Fjournal.pcbi.1002202

For this reason we have closed your question. This allows us to keep the site focused on the topics that the community can help with.

If you disagree please tell us why in a reply below, we'll be happy to talk about it.

Cheers!