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Generate a DB of protein protein interactions

Hello, I'm starting a new project related with protein protein interactions. I'm having some problemss trying to retrieve enough data to create my database for the train group.

My main goal is to generate a database of interacting proteins with known 3D interacting structure and know if those interactions are modified by any mutation.

From now on I've been using the db of Shagni et al. 2015 but this is not enough and I don't know where to find the data

Thank you all

ppi
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updated by Ram Ram • written by albert.castella.teruel • albert.castella.teruel

2 answers

Did you have a look at PDB ? Also PFAM developed something like this called iPfam.

Edit: What about Interactome3D ?

• 1 views • link
written by Jean-Karim Heriche Jean-Karim Heriche

Check this link. It has several links for different organisms and provide information on Protein-protein interactions.

And if you know any 2 proteins that interact with each other and you want to kow the interface residues, you can use http://cosbi.ku.edu.tr/prism/

This will provide the interaction network for two proteins.

Hope this helps.

• 1 views • link
updated by Ram Ram • written by ARB • ARB

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