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Transcriptional regulation through transcription factor (protein)

Hello everyone,

I have a list of transcription factors and their target genes, which I have downloaded from various online databases.I want to know that what kind of regulation exists between each TF-Gene pair, means weather it is upregulation, downregulation, coactivation etc.Is there any database or tool to find it? Please suggest.

Thanks

gene genome rna-seq

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