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performance assessment of gene regulatory networks

Hello all

Supposing I'm going to infer gene regulatory network with various methods (correlation-based, mutual information,regression and bayesian) for RNA-seq data sets but there is not a gold standard for Arabidopsis (my interest organism), then how I can evaluate the accuracy and performance of these methods to compare them?

Thanks

rna-seq grn

1 answer

The same way you evaluate anything else, find apparently meaningful differences between them and test them experimentally.

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