Steps For Designing An Exome Array, Best Practices Guidance?
Hello folks--
Recently I spotted a question about working with a new set of genomics data on the UCSC mailing list, and highlighted it on the blog. It was pretty popular.
Got a genome + transcriptome. Now what?
With that as the background, I got a subsequent question from Padraig about designing an exome array with this information. I haven't been involved with that personally, so I thought I would pose the question here:
What would your process be for designing a custom array for CHO? Got any steps, guidelines, known hazards, etc? How well assembled does it need to be? How well annotated?
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