Thanks so much for your email, I am really appreciate that. I am statistician doing a PhD on the area of DNA methylation, I have devolve statistical test for testing significant between two condition for example cases and control at same tissue .

I need your help to simulate 1000 gene, each gene greater than or equal 20 CpG. And at least 3 sample per group. Same tissue I am looking for exist code can do that or real data in the percentage Methylation format including (chr #, position, Gene names)