Obtain heterozyous/IUPAC consensus sequences from multiple sequence alignment
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8.8 years ago
Louis Kok ▴ 30

Hi all,

I wonder if anyone has tried out something to obtain a consensus sequence with IUPAC code from multiple sequence alignment regardless of the percentage of the bases? For example, at a particular position, there are bases, G and R, which will eventually become a R. For A and T, a W will be the output. Gaps will be ignored for this case.

Appreciate if you could kindly share your idea on doing this.

Thanks a lot

multiple-sequence-alignment IUPAC heterozygous • 2.4k views
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