Viable pathway tool for T-Cell activation pathway identification
I have a list of genes that are of high expression in activated T-cells. I am looking for a good pathway tool to either identify the list of genes and their connections, or find a single pathway for one of the genes. So far I have had minimal luck using DAVID and reactome. I did however get some results through babelomics snow, I am just unsure how to continue with the data it has generated. I have looked through KEGG and biocarta as well, with minimal success. We are looking for protein effects on RNA processing of other target genes. Strings does a good job in showing relations, however we are less concerned with protein-protein interaction.
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I'm still confused about what you have and what you want. Can you clarify what you are trying to do?
Yes. We have a list of 13 proteins that showed high expression in Activated T-Cells vs. non activated T-cells. We are attempting to determine how these 13 proteins fit into a T-Cell activation pathway. We want to look at how the proteins act upon the rna, not on each other.