This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Beagle imputation output, incorrect genotype probability format?

After imputing with BEAGLE one of the markers (a deletion) doesn't have three genotype probabilities but instead just has a '1' written in its place.. usually there are three comma separated probabilities.. does anyone know if this is a bug in BEAGLE?

##INFO=<ID=AR2,Number=1,Type=Float,Description="Allelic R-Squared: estimated correlation between most probable ALT dose and true ALT dose">
##INFO=<ID=DR2,Number=1,Type=Float,Description="Dosage R-Squared: estimated correlation between estimated ALT dose [P(RA) + 2*P(AA)] and true ALT dose">
##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">
##FORMAT=<ID=DS,Number=1,Type=Float,Description="estimated ALT dose [P(RA) + P(AA)]">
##FORMAT=<ID=GP,Number=G,Type=Float,Description="Estimated Genotype Probability">
CHR    POS              ID      REF  ALT   QUAL FILTER INFO                   FORMAT         1111    2222   3333   4444
Chr1    51058623        .       A       .       .       PASS    AR2=0;DR2=0     GT:DS:GP        0|0:0:1 0|0:0:1 0|0:0:1 0|0:0:1
beagle imputation sequence

0 answers

No answers yet.

Log in to answer this question.