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convert pseudogene IDs in Gencode releases to HGNC gene symbols

The pseudogene file I downloaded from GeneCode looks like this:

chr10   Yale_UCSC       transcript      5304431 5304865 .       -       .       gene_id "PGOHUM00000289731"; transcript_id "PGOHUM00000289731"; gene_type "pseudogene"; gene_status "UNKNOWN"; gene_name "PGOHUM00000289731"; transcript_type "pseudogene"; transcript_status "UNKNOWN"; transcript_name "PGOHUM00000289731"; level 3; tag "2way_pseudo_cons"; yale_id "PGOHUM00000289731"; ucsc_id "NM_000987.3-9"; parent_id "ENSG00000161970";
chr10   Yale_UCSC       transcript      6071517 6071921 .       -       .       gene_id "PGOHUM00000289732"; transcript_id "PGOHUM00000289732"; gene_type "pseudogene"; gene_status "UNKNOWN"; gene_name "PGOHUM00000289732"; transcript_type "pseudogene"; transcript_status "UNKNOWN"; transcript_name "PGOHUM00000289732"; level 3; tag "2way_pseudo_cons"; yale_id "PGOHUM00000289732"; ucsc_id "NM_000994.3-10"; parent_id "ENSG00000144713";
chr10   Yale_UCSC       transcript      6293104 6294274 .       -       .       gene_id "PGOHUM00000289733"; transcript_id "PGOHUM00000289733"; gene_type "pseudogene"; gene_status "UNKNOWN"; gene_name "PGOHUM00000289733"; transcript_type "pseudogene"; transcript_status "UNKNOWN"; transcript_name "PGOHUM00000289733"; level 3; tag "2way_pseudo_cons"; yale_id "PGOHUM00000289733"; ucsc_id "NM_001007070.1-2"; parent_id "ENSG00000137575";
chr10   Yale_UCSC       transcript      7295121 7295279 .       -       .       gene_id "PGOHUM00000289735"; transcript_id "PGOHUM00000289735"; gene_type "pseudogene"; gene_status "UNKNOWN"; gene_name "PGOHUM00000289735"; transcript_type "pseudogene"; transcript_status "UNKNOWN"; transcript_name "PGOHUM00000289735"; level 3; tag "2way_pseudo_cons"; yale_id "PGOHUM00000289735"; ucsc_id "NM_004374.3-4"; parent_id "ENSG00000164919";

How do I convert the gene_id (e.g PGOHUM00000289731) to HGNC symbols? Biomart and BioDBnet do not seem to offer this

pseudogene gene genecode

1 answer

You can probably download the complete HGNC dataset. Here the "pseudogene.org" column contains gene ids similar to your ones. You might want to write a small program to get corresponding hgnc symbols.

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