Hi there,

In variant annotating with SnpEff + dbNSFP, there are many variants assigned with more than one value in some fields. For example, as highlighted in yellow as below, SIFT_Pred has 5 "T" (but only one SIFT_Score), Polyphen2_HDIV_pred has 2 "B".

If I understand it correctly, each variant should only have one SIFT_score, SIFT_Pred, etc. Did I miss anything?

Thanks in advance.

7    140301731    .    G    T    2918.77    PASS    AC=2;AF=1.00;AN=2;DP=95;FS=0.000;MLEAC=2;MLEAF=1.00;MQ=60.00;MQ0=0;POSITIVE_TRAIN_SITE;QD=30.72;VQSLOD=6.96;culprit=FS;ANN=T|missense_variant|MODERATE|DENND2A|ENSG00000146966|transcript|ENST00000275884|protein_coding|2/19|c.467C>A|p.Pro156His|885/3735|467/3030|156/1009||;dbNSFP_rs_dbSNP141=rs269243;dbNSFP_CADD_phred=11.67;dbNSFP_ESP6500_AA_AF=0.989765;dbNSFP_ExAC_AF=9.549e-01;dbNSFP_UniSNP_ids=rs269243,rs1681775,rs52835101,rs58245328,rs269243;dbNSFP_SIFT_pred=T,T,T,T,T;dbNSFP_Polyphen2_HDIV_rankscore=0.02656;dbNSFP_Polyphen2_HDIV_pred=B,B;dbNSFP_ESP6500_EA_AF=0.936014;dbNSFP_SIFT_converted_rankscore=0.12818;dbNSFP_Polyphen2_HVAR_rankscore=0.01281;dbNSFP_1000Gp1_AF=0.9647435897435898;dbNSFP_Polyphen2_HVAR_pred=B,B    GT:AD:DP:GQ:PL    1/1:0,95:95:99:2947,286,0