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microarray data sets


I collected 3 datasets with different platforms. My interest is to find out target genes using bioinformatics tools and some data mining approaches. But i am little bit confuse on how to validate my result without wet lab approaches..???

gene

Thanks... If possible Can you please refer me some journal on that ????

Perhaps you can find a review article somewhere, this is more the sort of thing you'd find in a text book.

1 answer

Your options are:

  1. Find a dataset with known positive/negative results and run that through your prediction to see how close the results are.
  2. Do cross validation (or similar), though you might need more datasets.

Option 2 isn't really validation in the strictest sense, but it's as close as you can get without additional experiments.

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