Hi all
I am generating a gVCF file from Isaac Variant Caller and it outputs a gVCF file with all the non variant sites as blocks and I want to break the blocks into single variants line.
There is a way to do this using a BED file so the question is where can a BED file be found for the entire genome OR can this be accomplished without a BED file?
Any help will be highly appreciated.
Is this for the whole human genome? Breaking the a whole genome gVCF into a per-nucleotide VCF would result in a very large file.