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Calculating Watterson's Theta and Tajima's Pi from NGS (bam file)

Hello,

I am currently using PoPoolation to calculate Tajima's Pi and Watterson's Theta from my reference aligned reads (bam file). However, even at 100x coverage the script is slow, can take several days to parse one 160kb contig.

Any ideas on faster tools? I am working with non model organisms.

Adrian

ngs theta pi bam snp

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