Metabolite PLS-DA analysis bad p-value

Hi All,

I'm doing some metabolomics analysis using the web based tool available from http://www.metaboanalyst.ca/

For the PLS-DA analysis my samples good separtion, however the permutation p-value is bad. I'm very new to this kind of analysis, and I'm not sure if I'm making some mistakes. Can permutation values be bad if separation between samples are good? Moreover as the PLS-DA model is bad, can I use the metabolites with VIP values >1.0? Or are these VIP values useless as well?

For bigger sized image please click on the following link:

http://postimg.org/image/s73wsx71h/

Thanks

metabolomics pls-da

• 3,990 views • link

updated 4.5 years ago by Ram

• written 11.8 years ago by The

Hi, the link you posted (http://[url=http://postimg.org/image/s73wsx71h/][img=http://s10.postimg.org/s73wsx71h/PLS_DA_combined.jpg][/url]) was broken. I tried correcting it, but it didn't work out. The underlying image is too small. Could you maybe edit the question correct the link please? Thank you!

• 0 views • link

written 11.8 years ago by Ram

Hello, I've edited the links

• 0 views • link

written 11.8 years ago by The

Thank you, that should help!

• 0 views • link

written 11.8 years ago by Ram

1 answer

Hi,do you figure out whether you can use the VIP value in this case?

• 1 views • link

written 11.4 years ago by wenbo •