Entering edit mode
9.6 years ago
Ginsea Chen
▴
130
Hello everyone
I tried to use some known sequences as query database to search whole members of special gene family in whole genome database through BLAST and HMM. There were many sequences were obtained with different length of domain and sequence.
The problem is high variation among length of different domain, e.g. the smallest domain length in sequence is 45 aa and the highest domain length is 225 aa.
Some candidate sequences should be deleted as the variation length, but I don't how to choose a suit screening criteria.
If you have some suggestions, please teach me, thanks for your help!
