full length Protein modelling
Hi,
I am trying to create a protein model using swissmodel. The problem is that it only creates model that are the same length as the template. How do I create a model that includes a histidine tag and the rest of the sequences on the C terminus that are not present in the template.
James
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jameschegek •
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C-terminal His-tags are frequently too disordered to appear in experimental structures, so it's unlikely that they can be modelled - and if they can, even less likely that the model will be meaningful.
By definition you cannot "homology model" beyond the limits of the template