How Does Multiple Genome Alignment Work?
Hi Everyone,
I'm wondering how multiple genome alignment works. From what i've read, an algorithm goes through all the genomes and finds matching regions between all of them. How do they use these matching regions to infer the path that evolution took to differentiate the species?
• 2,143 views
•
link
updated
by
linus
•
written
by
nelson.liu.2009 •
•
written
by
nelson.liu.2009 •
1 answer
Here is a paper about Mauve. I think one of the most used multi-genome aligners. In the "Methods" section they write how their algorithm works.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC442156/
I hope it is not behind a paywall.
Log in to answer this question.
More posts like this
-
running RAxML and MrBayes over concatinated multiple sequence alignments
written by Moses
-
How to construct phylogeny based on multiple sequence alignment of orthologs without assembling the…
written by abbhinay •
-
Finding a orthologous genes between human and mouse along with percent alignment?
written by wangfx •
-
Identify informative markers from two in silico digests?
written by J.R. •
-
GATK vs more traditional SNP and alignment tools
written by anjali.gopal91 •
-
Finding miRNA & small RNA that are human-specific?
written by Adamc
-
PAML CodeML Branch Site Model for Positive Selection
written by courtney1cheng •
-
PAML CodeML Branch Site Model for Positive Selection
written by courtney1cheng •
-
VCF filtering with a maximum coverage threshold
written by rwn
-
Epo Pipeline, From Genome Fasta Files To Multiple Genome Alignment Output
written by Lds •
