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Is there an software can handle CNV analysis without control for WES data?

Does control-freec can handle it?

I found it in a paper?

but when using it,i got this error:

ERROR: Currently you need to provide a control sample ('mateFile' or 'mateCopyNumberFile') when you analyze targeted sequencing data to eliminate capture bias. The GC-content bias is not the only bias in targeted sequencing.

anyone know why?

software error

1 answer

how about cn.mops?

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