Has anyone used GET_HOMOLOGUES

Question

[Sujai Kumar]

Has anyone used GET_HOMOLOGUES for pan-genome protein conservation/ortholog analysis? http://www.ncbi.nlm.nih.gov/pubmed/24096415 It's supposedly better than orthoMCL?

If you have used it - would you mind sharing your opinion of it and if you'd prefer it to orthoMCL (and why).

Thanks!

Answer 1

[bcontreras]

Hi Sujai, I'm Bruno Contreras, one of the authors.

If you're still there, the main advantage is that you can use and combine 3 different clustering algorithms and the perform several downstream analyses, as explained in the manual and tutorial at https://github.com/eead-csic-compbio/get_homologues ,

cheers,
Bruno