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Methods to determine if a nanopore 1-D read is from the forward or reverse strand without a reference?
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14 months ago

I am guessing the answer is no, but would it be theoretically possible to do so?

nanopore • 117 views
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9 months ago
Belgium

No, that's not possible. There is no biological or biochemical difference those strands, it's just an arbitrary convention based on the reference genome.

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