Entering edit mode
5.2 years ago
lokdeep17
•
0
I am trying to use PAML for the first time, and I am like Alice falling in Rabbit's hole. I tried to understand it using some online tutorials, but I am not sure if I understood it correctly. I want to check for positive selection for a gene in different species. Can someone please give me a step-wise guide with an easy explanation to use it. Furthermore, I also want to know how to interpret the results. Thank You very much!
I think you have to start from this post.
Help For Paml About The Positive Selection
and study PAML-manual.
(the following post)
A: dN/dS ratio (omega)
Did you search the Biostars-site? There are a lot
of posts about this problem.
To search it, go to the left-hand upper corner of the main page,
press LATEST and type your question in the empty string of the
next page. After that look at the right panel - there will be
a lot of related posts in addition to your findings in the middle of the page.