Looking For Tutorial Reference On Sequencing And Alignment

Question

[Fixee]

I know the basic terms from high school biology: nucleotide, base, base pair, centromere, nucleic acid, etc.

But the "newer" terms common on this forum for describing the technology around sequencing and alignment are foreign to me: chimeric reads, clipped alignment, lane, etc.

Can anyone suggest a good tutorial reference that describes terms akin to the above? Are there references for computer scientists who are not biologists?

Note: I have read "The Processes of Life" by Hunter, which is aimed at non-biologists, but it does not spend much time on sequencing technology.

Answer 1

[toni]

For all the terms linked to sequencing technologies (lane, flowcell, cycle, mate pairs...) either for Illumina, Roche 454 (...) you can go to [?]SeqAnswers forums[?]. Detailed tutorials (pdf) are available. You will find useful information on the Bioinformatics algorithms as well.

[toni]

Browsing this site (Biostar) could drive you to useful ressources !