adj p-value for meta-analysis

Question

[Edalat]

I did meta-analysis by metaRNAseq package,it used adj p-value( method="BH"),should I convert adj p-value to fdr adj p-value or not? if yes,what package do you suggest?

[Fabio Marroni]

If it used BH it is already FDR. You can give a look at the documentation of p.adjust here

[ATpoint]

I don't understand the question. You get a FDR adjusted p out of your pipeline, so why further converting it?

[Edalat]

no,I got adjusted p-value. I mean should I convert them to FDR adj p-value for high accuracy?or adjusted p-value have high accuracy?

Answer 1

[ATpoint]

What you think are two different values are actually the same thing. Use the p value that you already have. It has already been adjusted for FDR by BH, stands for Benjamini Hochberg method for false discovery rate adjustment. You are fine.