Deleted:How to creat mutation profiles from TCGA MAFs

Question

[Erica]

Hi all,

I met a problem when I read the paper :https://www.ncbi.nlm.nih.gov/pubmed/?term=27333808

The authers use mutation profiles to build a method for identifying cancer driver genes and the data is from TCGA. As far as I know, the mutation files in TCGA are MAF files. What should I do to change the MAF into a mutation profile with each row represents a gene and each column represents a patient.

Thank you!