How to draw lego plot Using Mutation Data (MAF format input)?

Question

[pradyumna Jayaram]

Hi all,

I found an article on nature (http://www.nature.com/ng/journal/v45/n5/full/ng.2591.html) where Lego plots were shown which represents mutation frequencies of the samples. How do I replicate the similar kind of graph with the data I have?

I found that MutSigCV can be used to plot the similar graph. But the input data I have is simple maf(mutation annotation format) file. Can lego plot be drawn with the data? Is it possible with any R scripts? please share if some one have any idea.

Thanks in Advance.

Pradyumna

[Irsan]

I would advice against it. Becuase of the three dimensions, some bars can block others.

Answer 1

[poisonAlien]

Here