study power / sample size estimation for GWAS

Question

[tarek.mohamed]

Hi,

Is there a way by which I can calculate GWAS power / required sample size?

Thanks

Answer 1

[WouterDeCoster]

Highly dependent on the expected effect size/odds ratio and population frequency, so without estimating those probably not.

Have a look at: http://pngu.mgh.harvard.edu/~purcell/gpc/