Assigning time to data analysis (detection of signatures of selection)

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7.8 years ago

serpalma.v ▴ 80

Dear community We are currently writing a grant proposal where we intend to sequence the genome of 6 mouse lines with 10 individuals per line, then process the data to the point where we can detect signatures of selection by calculating iHS and FST statistics. (based on: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144660/)

I am proficient in R and basic user of Python and UNIX command line. I have no previous experience with this type of analysis. However, I have experience with RNAseq data analysis.

What would you advise as a reasonable timeframe? (we were predicting 6 months full time, but we are not sure if this is an underestimation)

SNP sequencing next-gen • 1.2k views

ADD COMMENT • link 7.8 years ago by serpalma.v ▴ 80

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Which sequencing technology will you use?

ADD REPLY • link 7.8 years ago by sentausa ▴ 650

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Ilumina HiSeq 2000, 30x coverage

ADD REPLY • link 7.8 years ago by serpalma.v ▴ 80

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