R code for variable methylation region identification (VMR, vmr)

Question

[Shicheng Guo]

Hi my colleagues,

Is there anyone can share a R code for variable methylation region identification.

Best regards,

VMR: http://epigenie.com/variable-methylation-regions-and-missing-heritability-with-dr-andrew-feinberg/

VMR: Nat Genet. 2009 Feb;41(2):178-86. doi: 10.1038/ng.298. Epub 2009 Jan 18

VMR: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729128/

champ.mvp: http://bioconductor.org/packages/devel/bioc/html/ChAMP.html

Significance: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276267/

You know, the formula or the code would be great helpful for the follower or the users.

[andrew.j.skelton73]

Are you looking for DMRs (Differentially methylated Regions)? or are variable methylation regions something different?

[Devon Ryan]

7 weeks later, but they're different. VMRs just show higher variation. These could be important for things like epigenetic inheritance.