Entering edit mode
8.9 years ago
r.monil
•
0
Hello all,
I'm new to bioinformatics. I have expression level data from Human Exon ST 1.0 that I want to transform to U133 Plus 2.0 expression level data. Can someone please point me towards the right direction? Is there an R package that does this? Where can I find information on U133 Plus 2.0 and Human Exon ST 1.0?
What do you mean by "transfer"? What is it that you want to do with the "transferred" data?
I want to "transform", not "transfer", the data.
From what I understand, U133 Plus 2.0 and Human Exon ST 1.0 are like two different 'platforms' or 'formats' for expression level data.of the same genes. I have been given expression levels on Human Exon ST 1.0 and I need to feed them into a function that performs some algorithm that's based on U133 Plus 2.0.
Can you be more specific about the algorithm. These two array platforms are quite different and an algorithm specifically designed for U133 Plus 2 will not likely work for Human Gene ST arrays.
The algorithm is a variation of partial deconvolution from the cellMix package: http://web.cbio.uct.ac.za/~renaud/CRAN/web/CellMix/vignettes/Introduction.pdf. I think the simplest way to describe the algorithm is that it's a form of regression.
Can you outline the differences between the two? Or better yet, can you point me to resources where I can find information on these differences?