Extract variability between coordinates

Question

[egustavsson]

Hi all,

Could anyone suggest how to extract variability within a range, i.e. candidate regions, from multiple vcf files?

I have exome data from a number of samples, as well as SNP array data, and I'm looking for recessive variability from the exome data within generated runs of homozygosity.

Thanks for your time

Answer 1

[Ashutosh Pandey]

Tabix can help you if you are looking for variants in a given genomic region (http://samtools.sourceforge.net/tabix.shtml)

[egustavsson]

Thanks Ashutosh, tabix will do exactly what I'm looking for.

[Ashutosh Pandey]

Ok great. Moving it to answer.