Closed:please evaluate my experiment design
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4.9 years ago
9521ljh ▴ 50

I have Whole Genome sequencing DNA data of children sarcoma tumor ( many types of sarcoma i have)

In research paper, i read the children are more affected by heredity factors than environment factors.

Thus, i'm gonna prepare Germline, Somatic calling pipeline, and also copy number.

additionally, based on the children cancer have long term cure need, I have necessity of finding recurrent mutation.

Thus i found the paper

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

and i'm gonna use tools or pipeline in that paper.

Because i'm the new on bioinformatics, i cannot sure what my plan is logically significant. Thank you.

SNP snp next-gen sequencing genome • 46 views
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