Question

Michigan imputation server quality control failed

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5.1 years ago

Phoenix Mu ▴ 100

I am using Michigan Imputation Server. I have performed a initial QC and removed monomorphic sites and sites with MAF > 0.5. However, the QC step on the server failed. There is no error message or logfile that I can check.

So I just do not know how to find out what is wrong with my VCF file.

imputation genotype • 2.5k views

ADD COMMENT • link updated 3.1 years ago by 4galaxy77 2.8k • written 5.1 years ago by Phoenix Mu ▴ 100

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Why did you remove MAF > .5?

ADD REPLY • link 4.0 years ago by curious ▴ 750

score 0 · Answer 1 · 2021-03-23

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3.1 years ago

binodregmi30 ▴ 10

ya! I am also wondering why to remove MAF>0.5?

ADD COMMENT • link 3.1 years ago by binodregmi30 ▴ 10

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Because it probably means there has been some kind of strand-flip.

ADD REPLY • link 3.1 years ago by 4galaxy77 2.8k