Looking for gene expression data from cultured human cells treated with drugs

Question

[chenyangls]

Hi All,

I'm trying to get gene expression data from human cell lines before and after treated with drugs. I understand CMap contains such information, but the number of drugs is limited. Could you recommend other data sources, especially for cancer drugs?

Thanks

Answer 1

[David Quigley]

I'd start with the Wellcome Trust's genomics of drug sensitivty dataset and the Broad/Novartis CCLE datasets. You may also be interested in Haibe-Kains et al. Nature 2013, which raised concerns about how consistent these two collections are with each other.

Answer 2

[networkbiothings]

Biogps (http://biogps.org) also has a number of datasets of interest in its library (http://biogps.org/dataset/)